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  • 產(chǎn)品名稱： αvβ1 integrin-IN-1
  • 產(chǎn)品貨號(hào)： CST13473
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購(gòu)： 800
  • 數(shù)量：
    庫(kù)存： 5
  • 規(guī)格： 10mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    產(chǎn)品描述
    αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.
    靶點(diǎn)活性
    αvβ1 integrin:0.63 nM , αvβ1 integrin:0.63 nM
    體外活性
    In a murine model of liver and lung fibrosis, the administration of αvβ1 integrin-IN-1 leads to a significant reduction in the expression of fibrotic markers.[1]
    分子量
    558.65
    分子式
    C26H34N6O6Sicon
    化學(xué)結(jié)構(gòu)

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    CAS No
    1689540-62-2
    存儲(chǔ)
    Powder: -20°C for 3 years | In solvent: -80°C for 2 years
    溶解度
    DMSO: 5.59 mg/mL (10 mM)
    ( < 1 mg/mL refers to the product slightly soluble or insoluble )
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    參考文獻(xiàn)
    1. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett. 2016 ; 7(10):902-907.
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    Note
    For research use only.